|
| 產(chǎn)地 | 進口、國產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號 | CS12158 |
| 應用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS編號 | |
| 抗體名 | Anti-SCRO/DCUN1D1 |
| 克隆性 | 是 |
| 靶點 | 詳見說明書 |
| 適應物種 | 詳見說明書 |
| 形態(tài) | 詳見說明書 |
| 宿主 | 詳見說明書 |
| 亞型 | IgG |
| 標識物 | 詳見說明書 |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1 |
中文名稱 鱗狀細胞相關蛋白抗體規(guī)格
英文名稱 Anti-SCRO/DCUN1D1
別 名 DCN1 defective in cullin neddylation 1 domain containing 1; DCN1 like protein 1; DCUN1 domain containing protein 1; DCUN1L1; Defective in cullin neddylation protein 1 like protein 1; RP 42; RP42; RP42 homolog; SCCRO; SCRO; Squamous cell carcinoma related oncogene; Tes 3; Tes3.
產(chǎn)品屬性：
鱗狀細胞相關蛋白抗體規(guī)格 濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit
產(chǎn)品類型 一抗
研究領域 細胞生物 細胞生物標志物
蛋白分子量 predicted molecular weight: 29kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human SCRO/DCUN1D1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
鱗狀細胞相關蛋白抗體規(guī)格 產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 DCUN1D1 (DCUN1 domain-containing protein 1) contains a DUF298 domain and a UBA-like ubiquitin. Forms part of an E3 ubiquitin ligase complex for neddylation. Required for neddylation of cullin components of E3 cullin-RING ubiquitin ligase complexes by enhancing the rate of cullins neddylation. Functions to recruit the NEDD8-charged E2 enzyme to the cullin component. Involved in the release of inhibitory effets of CAND1 on cullin-RING ligase E3 complex assembly and activity. Acts also as an oncogene facilitating malignant transformation and carcinogenic progression. Defects in DCUN1D1 may be a cause of squamous cell carcinomas.
Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
Subunit : Part of an E3 complex for neddylation composed of cullins, RBX1, UBE2M and CAND1. Interacts (via the C-terminus 50 AA) with CUL1, CUL2, CUL3, CUL4 and CUL5. Binds neddylated CUL1. Interacts (via the C-terminus 50 AA) directly with RBX1. Interacts preferentially with UBE2M-NEDD8 thioester (via N-terminus 1-26 AA) than with free UBE2M. Interacts with CAND1 when in complex with CUL1-RBX1.
Tissue Specificity : Expressed in pancreas, kidney, placenta, brain and heart. Weakly or not expressed in liver, skeletal muscle and lung. Strongly overexpressed in thyroid tumors, bronchioloalveolar carcinomas, and malignant tissues of squamous cell carcinoma of the oral tongue. Not overexpressed in aggressive adrenocortical carcinomas.
Similarity : Contains 1 DCUN1 domain.
Contains 1 UBA-like domain.
實驗流程：
全、新、優(yōu)、品、好四大特點：
鱗狀細胞相關蛋白抗體規(guī)格 全：公司提供上萬種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標準品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質量好，投訴比較少。
好：我公司具有優(yōu)質的技術團隊，產(chǎn)品一旦售出，實驗過程中遇到困難可提供在線技術咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
技術外包服務:
★鱗狀細胞相關蛋白抗體規(guī)格 分子生物學：質粒抽提、PCR、Q-PCR、RT-PCR、分子生物學：基因合成、引物合成、基因測序、載體構建等
★蛋白工程：原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程：細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構建、細胞RNAi技術等等。
正在熱銷的相關產(chǎn)品：
sal樣蛋白4 多克隆抗體 SALL4 Polyclonal Antibody 700/30ul#1540/100ul#2520/200ul
組蛋白去乙酰化酶復合亞基SAP30 多克隆抗體 SAP30 Polyclonal Antibody 700/30ul#1540/100ul#2520/200ul
GTP結合蛋白SAR1A 多克隆抗體 SAR1A Polyclonal Antibody 700/30ul#1540/100ul#2520/200ul
不育與TIR基序域含蛋白1 多克隆抗體 SARM1 Polyclonal Antibody 700/30ul#1540/100ul#2520/200ul
抗原3 多克隆抗體 SART3 Polyclonal Antibody 700/30ul#1540/100ul#2520/200ul
溶血磷脂?；D移酶抗體 轉錄因子sox9a抗體
磷酸化Ack1抗體 轉錄因子SOX17抗體
磷酸化β抑制蛋白1抗體 轉錄因子SOX-11蛋白抗體
磷酸化有絲分裂激酶A抗體 轉錄因子SOX10抗體
磷酸化APS抗體 轉錄因子RPF1抗體
轉移生長因子β2抗體（TGFβ2） ANGEL2蛋白抗體
轉移生長因子β3抗體（TGFβ3） ANGEL1蛋白抗體
轉移生長因子β受體2抗體（TGF-βRⅡ，TGFβRⅡ） AN1型鋅指蛋白5抗體
轉移生長因子β受體1抗體（TGF-βRⅠ，TGFβRⅠ） AMPK的相關蛋白激酶5抗體
甲狀腺過氧化物酶抗體 Alpha清蛋白抗體
云南紅豆杉Taxus yunnanensis Ponasterone A 松甾酮A 13408-56-5 C27H44O6 ≥95%
刺芒柄花苷OnonisspinoscglycosidqHPLC≥98%，20mg/支
環(huán)氧木香內酯 1343403-10-0 20mg HPLC≥98% 環(huán)氧木香內酯 1343403-10-0
中藥對照藥材檳榔花121390-200401TLC法鑒別
Escin IB;Aescin IB七葉皂苷B(IB)純度：≥95%
鱗狀細胞相關蛋白抗體規(guī)格補骨脂 Psoralea Corylifolia L. Psoralidin 補骨脂定 18642-23-4 C20H16O5 ≥98%
澤瀉醇B醋醋酯clisolBccqtctq20mg/支
苷;槲皮素-3-O-槐糖苷 Quercetin-3-O-sophoroside 18609-17-1 20mg HPLC≥98% 用于含量測定
中藥對照藥材紫花地丁121429-200501TLC法鑒別
Pseudolaric acid B-O-β-D-glucopyranoside土荊皮乙酸-O-β-D-葡萄糖苷純度：≥97%
