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產(chǎn)地 | 進口、國產(chǎn) |
品牌 | 上海莼試 |
保存條件 | Store at -20 °C |
貨號 | CS11872 |
應用范圍 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500 |
CAS編號 | |
抗體名 | Anti-TEM1/CD248 |
克隆性 | |
靶點 | 詳見說明書 |
適應物種 | 詳見說明書 |
形態(tài) | 詳見說明書 |
宿主 | 詳見說明書 |
亞型 | IgG |
標識物 | 詳見說明書 |
濃度 | 1mg/1ml% |
免疫原 | KLH conjugated synthetic peptide derived from human TEM 1 |
中文名稱 內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體說明書
英文名稱 Anti-TEM1/CD248
別 名 Tumor endothelial marker 1 precursor; TEM 1; TEM-1; tumor endothelial marker 1; CD248; Endosialin; Tumor endothelial marker 1; CD164L1; MGC119478; MGC119479. CD164 sialomucin-like 1; CD248_HUMAN.
產(chǎn)品屬性:
內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體說明書 濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來源 Rabbit
克隆類型 polyclonal
交叉反應 Human, Mouse, Rat, Dog, Pig, Cow, Horse
產(chǎn)品類型 一抗
研究領域 心 細胞凋亡 生長因子和激素
蛋白分子量 predicted molecular weight: 80kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TEM 1
亞 型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體說明書 產(chǎn)品應用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 IF=1:100-500
(石蠟切片需做抗原修復)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 The transmembrane glycoprotein Tumor endothelial marker 1 (TEM1) is highly expressed in tumor endothelial cells however it is barely detectable on normal endothelial cells. It is believed to play a role in tumor angiogenesis. It is expressed in stromal fibroblasts, metastatic hepatic lesions and during angiogenesis of corpus luteum formation and wound healing. TEM1 is being investigated as a potential target for cancer treatment.
Function : May play a role in tumor angiogenesis.
Subcellular Location : Membrane; Single-pass type I membrane protein (Probable).
Tissue Specificity : Expressed in tumor endothelial cells but absent or barely detectable in normal endothelial cells. Expressed in metastatic lesions of the liver and during angiogenesis of corpus luteum formation and wound healing. Expressed in vascular endothelial cells of malignant tumors but not in normal blood vessels. Expressed in stromal fibroblasts.
Post-translational modifications : O-glycosylated with sialylated oligosaccharides.
May be N-glycosylated.
Similarity : Contains 1 C-type lectin domain.
Contains 1 EGF-like domain.Contains 1 Sushi (CCP/SCR) domain.
Database links : UniProtKB/Swiss-Prot: Q9HCU0.1
內(nèi)皮唾液酸蛋白(CD248)是近年發(fā)現(xiàn)的人類標記物之一,在人類多種組織中異常高表達,內(nèi)皮唾液酸蛋白對細胞生長、生成、浸潤及轉(zhuǎn)移有重要作用。
實驗流程:
全、新、優(yōu)、品、好四大特點:
內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體說明書 全:公司提供上萬種產(chǎn)品,涵蓋了生物試劑,elisa試劑盒,標準品,培養(yǎng)基,原裝耗材,抗體、培養(yǎng)基、ATCC細胞等,基本上各種科研所需產(chǎn)品在我司都能找到。
新:產(chǎn)品更新速度較快,基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu):產(chǎn)品質(zhì)量好,投訴比較少。
好:我公司具有優(yōu)質(zhì)的技術團隊,產(chǎn)品一旦售出,實驗過程中遇到困難可提供在線技術咨詢。使您使用產(chǎn)品時沒有任何的后顧之憂。
技術外包服務:
★內(nèi)涎蛋白/內(nèi)皮唾液酸蛋白抗體說明書 分子生物學:質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學:基因合成、引物合成、基因測序、載體構建等
★蛋白工程:原核、哺乳動物蛋白表達系統(tǒng)等
★病毒包裝:腺病毒、慢病毒等
★抗體工程:磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細胞工程:細胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復、克隆形成)、細胞培養(yǎng)、細胞膜制備、穩(wěn)定細胞株構建、細胞RNAi技術等等。
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